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Evo-Gene

Evo-Gene

Decoding DNA

Created on 9th November 2025

Evo-Gene

Evo-Gene

Decoding DNA

The problem Evo-Gene solves

Problem We're Solving

The current process for genetic variant interpretation is a critical
bottleneck in personalized medicine.

Challenges: Current manual and data intensive analysis is plagued by:
long turnaround times (2 4 weeks), high operational costs ($200 --$500
per variant), and severely limited access to expert geneticists.

Uncertainty Crisis: The technology has outpaced our ability to interpret
it; consequently , 40 50% of patient genetic variants are classified as
"Uncertain Significance ( hindering diagnosis and treatment
planning.

High Stakes: This affects millions undergoing genetic testing for
diseases like cancer (e.g., a single BRCA1 mutation can increase breast
cancer risk by up to 85%), heart disorders, and rare genetic conditions,
demanding a rapid, scalable, and highly accurate AI solution.

Target Users

● Professionals aged 25- 55 in the healthcare, biotechnology, and research sectors.
● B2B, offering tools and APIs for labs, hospitals, and research institutions

Challenges we ran into

  • I faced a difficult bug with localStorage-based authentication where the app kept redirecting to the login page even after logging in.
  • The issue was caused by inconsistent client-side checks and timing problems due to Next.js rendering. I resolved it by moving all token checks into useEffect(), unifying the login validation logic, and adding redirect handling.
  • This made the authentication flow stable and seamless across the entire project.
  • We also faced problems while inferencing our model- Evo2 on MODAL.

Discussion

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